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PMDC NRE Step I guide

Applied anatomy for the NRE: lesions, nerves and congenital anomalies

NRE anatomy is applied: you identify the structure from a clinical picture. This page sets out the topics, the traps and a short revision plan.

Updated October 2026. 4 min read

Applied anatomy, including embryology and neuroanatomy, is about 6% of NRE Step I, roughly 12 of 200 items. PM&DC's published table shows 11 for anatomy in the legible part of the scan, and we scale the basic-science rows to the stated 60 items, so treat 11 to 12 as the range. The syllabus describes it as developmental anomalies, neuroanatomy and lesion syndromes, and regional or surgical anatomy. This is applied anatomy: the stem describes a patient with a nerve palsy, a lesion or a congenital anomaly, and you identify the structure involved. Diagram labelling is not the skill being tested.

6%of the paper
11 to 12items of 200
1 of 7basic-science domains

Weight and expected item count

Anatomy is joint-largest in the basic block with pathology, behind the clinical domains. Eleven to twelve items is about 12 minutes of paper time. Candidates often meet anatomy as a first-year subject and have not revised it since, so it is also where knowledge decay is greatest. The marks are recoverable because the high-yield core is small: neuroanatomy and lesion syndromes, peripheral nerve injuries, hernias and regional anatomy used in surgery, and embryological anomalies.

What is tested

BlockTopics
EmbryologyDevelopmental anomalies of the heart and great vessels; neural tube defects and nervous system anomalies; pharyngeal arches, thyroglossal duct and branchial cysts; gut rotation, herniation and congenital GI anomalies; urogenital development (horseshoe kidney, hypospadias, cryptorchidism)
NeuroanatomySpinal cord tracts and lesion syndromes (Brown-Sequard, syringomyelia); brainstem syndromes (Weber, Wallenberg, medial medullary); cranial nerve lesions; basal ganglia, thalamus, hypothalamus; circle of Willis and stroke territories; meninges, ventricles, CSF and venous sinuses; autonomic nervous system
LimbsBrachial plexus injuries and upper limb nerve palsies; lower limb nerve injuries, hip and knee clinical anatomy
Abdomen and pelvisInguinal canal, hernias, femoral triangle; abdominal vascular anatomy, portal-systemic anastomoses, peritoneal reflections; pelvic floor, perineum and pelvic organs
Thorax, head and neckMediastinum, pleura, bronchopulmonary segments, coronary anatomy; triangles of the neck, thyroid, parotid and facial nerve
ImagingSurface anatomy and radiological anatomy

Local guideline points

Anatomy has no national guideline in the way public health does, but two local features matter.

  • Surgical and trauma anatomy: Pakistani curricula emphasise the anatomy that surgeons use (inguinal region, neck, biliary tree, nerve injuries after fractures). Foreign curricula in Russian, Chinese and Central Asian programmes often cover the same material in a different order and with different naming. Check the names you know against the English terms in standard references such as Snell or Gray's.
  • Congenital anomalies: neural tube defects, congenital heart disease and hypospadias appear in embryology questions and link to paediatrics (folic acid, screening, early management). Learn them once, not twice.
  • English terminology: if you were taught anatomy in another language or with Latin-only nomenclature, make a short list of English clinical eponyms (for example the named lesion syndromes above) and practise them.

Three typical traps

  1. Knowing the pathway but not the level. Brainstem and cord stems test where a lesion sits from the pattern of deficits: which side, which modality, which cranial nerve. Practise by writing the deficit and then drawing the lesion, not by reading the pathway diagram.
  2. Naming the nerve but forgetting the sign. A nerve palsy stem describes wrist drop, claw hand, foot drop or loss of shoulder abduction. The answer depends on the sign and the injury site (mid-shaft humerus, fibular neck, surgical neck). Link each nerve to its injury and sign as one unit.
  3. Embryology as memorised dates. Stems ask which structure fails to develop in a given anomaly. Learn the derivatives of the pharyngeal arches, the fate of the gut tube and the origin of urogenital structures as a flow, not as weeks.

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How to revise it

SessionDo this
1Neuroanatomy lesions: spinal cord, brainstem, internal capsule, cranial nerves. Build one table: lesion, deficit, vessel.
2Brachial plexus and limb nerves: injury site, sign, muscle affected.
3Inguinal canal, femoral triangle, hernias, portal-systemic anastomoses, peritoneum.
4Head and neck: triangles, thyroid and parotid relations, facial nerve branches, venous sinuses.
5Embryology: heart, gut, urogenital system, pharyngeal apparatus, neural tube.
6Thorax and radiological anatomy: bronchopulmonary segments, coronary arteries, chest film landmarks; 30 mixed questions.

Most of the value comes from retrieval practice with clinical stems. Read an explanation only after you have attempted the question. The study plan places anatomy early so that it supports the clinical blocks.

Core facts to state without notes

  • Brown-Sequard syndrome: ipsilateral loss of motor function and of proprioception and vibration below the lesion, with contralateral loss of pain and temperature.
  • Lateral medullary (Wallenberg) syndrome: posterior inferior cerebellar artery territory; ipsilateral facial pain and temperature loss, contralateral body pain and temperature loss, Horner syndrome, dysphagia and ataxia.
  • Weber syndrome: midbrain lesion with an oculomotor palsy on the side of the lesion and contralateral hemiparesis.
  • Nerve injuries: radial nerve in the spiral groove gives wrist drop; axillary nerve at the surgical neck gives loss of shoulder abduction; common peroneal nerve at the fibular neck gives foot drop; Erb palsy (C5-6) gives the waiter's tip posture; Klumpke palsy (C8-T1) gives a claw hand.
  • Hernias: an indirect inguinal hernia passes lateral to the inferior epigastric vessels; a femoral hernia passes below and lateral to the pubic tubercle.
  • Portal-systemic anastomoses: lower oesophagus, anorectal junction, umbilicus and retroperitoneum; they explain varices, haemorrhoids and caput medusae.
  • Neck swellings: a thyroglossal cyst is midline and moves with tongue protrusion; a branchial cyst lies along the anterior border of sternocleidomastoid.

Anatomy supports surgery (hernias, trauma, vascular), medicine (neurology, stroke) and eye and ENT (head and neck). Treat the first year of the course as the foundation of the clinical years, which is how the examiners treat it.

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Frequently asked questions

How many anatomy questions are in NRE Step I?

PM&DC's published table shows 11 for applied anatomy in its legible rows. We scale the basic-science rows to the stated 60 items, giving about 12. Treat 11 to 12 as the range.

Does the NRE test diagrams or clinical anatomy?

PM&DC describes the questions as aimed at higher cognition, so anatomy is tested through clinical vignettes such as nerve injuries, lesion syndromes and congenital anomalies.

Which anatomy topics are highest yield?

Neuroanatomy and lesion syndromes, brachial plexus and limb nerve injuries, inguinal and femoral anatomy, head and neck anatomy, and embryological anomalies. This is our reading of the syllabus, not a frequency list.

Is embryology part of applied anatomy?

Yes. PM&DC's domain name is Applied Anatomy including embryology and neuroanatomy, and the syllabus lists developmental anomalies.

How long should I spend revising anatomy?

About six focused sessions of two to three hours with questions after each, plus short reviews in later weeks. Anatomy decays quickly, so repeat it near the end of your plan.

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